Datasheet
$199.00 – $429.00
Description
SFN (stratifin) is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.
Bioinformatics
| Weight | 1 lbs |
|---|---|
| Size | 20ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab WITHOUT BSA and Azide at 1.0mg/ml |
| Application | IHC |
| Symbol | SFN |
| Isotype | kappa, Mouse / IgG1 |
| Species Reactivity | Human. |
| Synonyms | YWHAS |
| Positive Control | A-431 cell lines., hTCEpi, PC-3 cells, Skin and tissues enriched in stratified squamous keratinizing epithelium. HaCaT |
| Cellular Localization | Cytoplasm and nucleus. May be secreted by a non-classical secretory pathway. |
| Mol. Weight of Antigen | 28kDa |
| Entrez Gene ID | 2810 |
| UniProt | P31947 |
| Clone | CPTC-SFN-2 |
| Supplied As | 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage and Stability | Antibody with azide – store at 2 to 8°C. Antibody without azide – store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| Categories | Cell Biology, Epigenetics, Neurosciences |
Additional Information
| Storage and Stability |
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
|---|---|
| Supplied As |
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Limitations |
This antibody is available for research use only and is not approved for use in diagnosis. |
| Warranty |
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product. |
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