Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
20ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Rabbit / IgG
Human. Does not react with Rat.
bowel, pancreas or pheochromocytoma., PC12 cells. Adrenal gland, thyroid
Finely granular cytoplasmic
|Mol. Weight of Antigen||
|Entrez Gene ID||
200ug/ml of recombinant MAb Purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
|Storage and Stability||
Antibody with azide – store at 2 to 8°C. Antibody without azide – store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cell Biology, Neurosciences